DNA replication complexes (replisomes) frequently encounter barriers that can eject them prematurely NAIL/DOMES from the genome.To avoid the lethality of incomplete DNA replication that arises from these events, bacteria have evolved "DNA replication restart" mechanisms to reload replisomes onto abandoned replication forks.The Escherichia coli PriA
Defining alternatives for non-renewable energy sources constitutes a priority to the development of our societies.One of these alternatives is biofuels production starting from energy crops, agricultural wastes, forest products or wastes.In this context, a "second generation" biofuels production, aiming at utilizing the whole plant, including ligno
Abstract Background Sepsis is a common cause of death in intensive care units worldwide.Due to the high complexity of this immunological syndrome development of novel therapeutic strategies is urgent.Promising drug targets or biomarkers may depict aquaporins (AQPs) as they regulate crucial key mechanisms of sepsis.Main body Here we report on base o
DNA glycosylase, as one member of DNA repair machineries, plays an essential role in correcting mismatched/damaged DNA nucleotides by cleaving the N-glycosidic bond between the sugar and target nucleobase through the base excision repair (BER) pathways.Efficient corrections Office Technology of these DNA lesions are critical for maintaining genome